The NeuroPatch
A flexible 2" x 11" patch worn on the upper back that simultaneously captures five physiological channels. Data streams continuously to the CALI clinical platform over Bluetooth LE without requiring patient interaction.
Technical Specifications
Real-Time Sensor Data
Five channels sampled simultaneously. Each signal stream feeds into the BiLSTM model as a distinct input feature for mood state deviation scoring.
Measures skin conductance driven by eccrine sweat gland activity. Reflects sympathetic nervous system arousal. Elevated values indicate increased autonomic activation associated with stress or mood state changes.
Measures electrical activity in the upper trapezius muscle. Captures muscle tension and sustained contraction associated with psychosomatic stress and agitation preceding mood episode onset.
Monitors peripheral skin temperature to detect thermoregulatory variation. Captures circadian phase shifts and temperature nadir disruptions that correlate with sleep-wake cycle changes in bipolar disorder.
Measures micromotion and body movement to quantify motor activity and postural agitation. Provides continuous actigraphy data correlated with psychomotor changes in bipolar disorder.
Electrochemical channel measuring cortisol concentration in sweat as a biochemical stress marker. Provides a proxy for HPA axis activation, complementing autonomic signals from EDA and EMG.
Clinical Relevance
Each sensor channel was selected based on peer-reviewed evidence linking physiological measurement to mood state in bipolar disorder. The combined signal profile enables detection of prodromal patterns before overt symptom onset.
- EDA captures sympathetic nervous system arousal at sub-second resolution. Elevated EDA correlates with autonomic activation preceding mood state transitions.
- EMG measures upper trapezius muscle activity. Sustained tension elevation above individual baseline is associated with psychosomatic agitation in bipolar disorder.
- Skin temperature monitoring detects peripheral thermoregulatory variation and circadian phase shifts correlated with sleep-wake disruptions preceding episode onset.
- Accelerometer quantifies micromotion and postural activity. Psychomotor agitation and activity suppression are both measurable as deviations from individual actigraphy baseline.
- Cortisol electrochemical channel measures sweat-based biochemical stress marker, providing HPA axis activation data to complement the autonomic signals from EDA and EMG.
See NeuroPatch in Action
Explore the live clinical dashboard or request a demonstration with your team.